Vaginal Acidity Affects Vaginal Microbiota in Postmenopausal Women

BACKGROUND: The changes in vaginal acidity impact the composition of microbiota, either commensal or pathogenic. After menopause, tract is more susceptible to infection. Current study was conducted analyze effect on microbiota menopausal women.METHODS: A cross-sectional 32 subjects with vulvovaginal atrophy (VVA). Vaginal pH measured using a strip colorimetric examination. detection Candida sp. done by 10% potassium hydroxide. Meanwhile for Trichomonas vaginalis, Gardnerella Lactobacillus iners, and crispatus, polymerase chain reaction performed. data were statistically analyzed.RESULTS: G. vaginalis mostly found pathogenic microorganism current (40.63%), followed (25%). Further analysis showed that L. crispatus positive samples 9 cases iners cases. had an increased risk at ≥6 (OR=8.273), T. reduced (OR=0.765), (OR=1.440), (OR=0.077), while (OR=1.111).CONCLUSION: alterations postmenopausal women affect composition. decrease number increase microorganisms line pH.KEYWORDS: Lactobacillus, microorganisms,